"rewrite" structure for subdomain on Nginx

I want to do a custom rewrite for the subdomain on ISPconfig. When I add the code below for this, the subdomain is redirected to the main domain.

Sample #1:

server {
  ...
     if ($http_host = "panel.example.com") {
         rewrite ^(?!/(_SubDomains/Panel|stats|\.well-known/acme-challenge))/(.*)$ /_SubDomains/Panel/$2 last;
         rewrite ^/(.*)/(.*)$ /index.php?cmd=$1&scd=$2? last;
      }
  ...
 }

If I do as in example two, Nginx server does not work.

Sample #2:

server {
...
     if ($http_host = "panel.example.com") {
         rewrite ^(?!/(_SubDomains/Panel|stats|\.well-known/acme-challenge))/(.*)$ /_SubDomains/Panel/$2 last;
         location ~ \.php$ {
                 rewrite ^/(.*)/(.*)$ /index.php?cmd=$1&scd=$2? last;
         }
     }
...
}

I was using in Apache server like this:

<IfModule mod_rewrite.c>
    SetEnv HTTP_MOD_REWRITE On
        RewriteEngine on
        RewriteBase /
        RewriteCond %{REQUEST_URI} !\.php$ [NC]
        RewriteCond %{REQUEST_URI} [^/]$
        RewriteRule ^(.*)$ $1.php [L]
        RewriteCond %{REQUEST_FILENAME} -d [OR]
        RewriteCond %{REQUEST_FILENAME} -f [OR]
        RewriteCond %{REQUEST_FILENAME} -l
        RewriteCond %{REQUEST_URI} !.(css|gif|ico|jpg|js|png|swf|txt)$
        RewriteRule ^ - [L]
        RewriteRule ^([^/]+)/([^/]+)?$ index.php?cmd=$1&scd=$2 [L,QSA]
        RewriteRule ^([^/]+)/?$ index.php?cmd=$1 [L,QSA]
</IfModule>

Without rewrite link: https://panel.example.com/index.php?cmd=abc&scd=xyz

With Rewrite: https://panel.example.com/abc?scd=xyz

How can I use it on Nginx PHP-FPM server like I use it on Apache server in subdomain?