Pip packages are installed but not working

I'm new to ubuntu and I've installed many packages via pip but they don't work and give me this error.

zsh: command not found: ipython

I have tried many ways, but after logout and login, I get the same error until I enter source ~/.profile, and then it works correctly.

~/.profile

# ~/.profile: executed by the command interpreter for login shells.
# This file is not read by bash(1), if ~/.bash_profile or ~/.bash_login
# exists.
# see /usr/share/doc/bash/examples/startup-files for examples.
# the files are located in the bash-doc package.

# the default umask is set in /etc/profile; for setting the umask
# for ssh logins, install and configure the libpam-umask package.
#umask 022

# if running bash
if [ -n "$BASH_VERSION" ]; then
    # include .bashrc if it exists
    if [ -f "$HOME/.bashrc" ]; then
    . "$HOME/.bashrc"
    fi
fi

# set PATH so it includes user's private bin if it exists
if [ -d "$HOME/bin" ] ; then
    PATH="$HOME/bin:$PATH"
fi

# set PATH so it includes user's private bin if it exists
if [ -d "$HOME/.local/bin" ] ; then
    PATH="$HOME/.local/bin:$PATH"
fi

I also added export PATH=~/.local/bin:$PATH to the end of the .profile file in the home directory and edited /etc/skel/.profile it didn't help me too.

any help is highly appreciated