Unmet dependencies on Asus

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I have a problem with the following: there is a little red circle with a minus sign in the top bar. When I click it, it opens a box with the following message in it:

An error occurred, please run Package Manager from the right-click window or apt-get in a terminal to see what is wrong. The error message was:
'Error: opening the cache (E:can not open /var/lib/apt/lists/security.ubuntu.com_ubuntu__dists__focal-security_InRelease-fopen (13:Permission denied), E: The package lists or status file could not be parsed or opened.)'.This usually means that your installed packages have unmet dependencies.

I don't have a lot of experience using ubuntu, or linux in general, and I don't know what this means. I ran apt-get in the terminal, but it didn't do anything, and I had no idea what run the Package Manager from the right click window meant.

Do you have any suggestions on what I should do?

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