Windows 10 VM guest OS boots to a blue screen after restarting the host

I used Ubuntu 20.04 as host and create a Windows 10 VM (21H1) in KVM (via the GUI). In the VM I pass my graphics card (RTX2070) and the whole group via PCI passthrough, which works thanks to various guides.

After I installed updates/drivers in the VM, the graka is also recognized. I can also install programs or restart the VM without any problems, but as soon as I restart the host (with the VM switched off), the Windows 10 VM boots into a blue screen (TDR Video Failure).

Here is my XML for the Windows 10 VM:

domain type="kvm">
  <name>win10</name>
  <uuid>39bd2708-4c4e-4ce4-8ef9-e8d322214990</uuid>
  <metadata>
    <libosinfo:libosinfo xmlns:libosinfo="http://libosinfo.org/xmlns/libvirt/domain/1.0">
      <libosinfo:os id="http://microsoft.com/win/10"/>
    </libosinfo:libosinfo>
  </metadata>
  <memory>8388608</memory>
  <currentMemory>8388608</currentMemory>
  <vcpu>4</vcpu>
  <os>
    <type arch="x86_64" machine="q35">hvm</type>
    <boot dev="hd"/>
  </os>
  <features>
    <acpi/>
    <apic/>
    <hyperv>
      <relaxed state="on"/>
      <vapic state="on"/>
      <spinlocks state="on" retries="8191"/>
      <vendor_id state="on" value="1234567890ab"/>
    </hyperv>
    <kvm>
      <hidden state="on"/>
    </kvm>
    <vmport state="off"/>
  </features>
  <cpu mode="host-model"/>
  <clock offset="localtime">
    <timer name="rtc" tickpolicy="catchup"/>
    <timer name="pit" tickpolicy="delay"/>
    <timer name="hpet" present="no"/>
    <timer name="hypervclock" present="yes"/>
  </clock>
  <pm>
    <suspend-to-mem enabled="no"/>
    <suspend-to-disk enabled="no"/>
  </pm>
  <devices>
    <emulator>/usr/bin/qemu-system-x86_64</emulator>
    <disk type="file" device="disk">
      <driver name="qemu" type="qcow2"/>
      <source file="/var/lib/libvirt/images/win10.qcow2"/>
      <target dev="sda" bus="sata"/>
    </disk>
    <disk type="file" device="cdrom">
      <driver name="qemu" type="raw"/>
      <source file="/home/bob/Downloads/Win10_21H1_German_x64.iso"/>
      <target dev="sdb" bus="sata"/>
      <readonly/>
    </disk>
    <controller type="usb" index="0" model="qemu-xhci" ports="15"/>
    <interface type="network">
      <source network="default"/>
      <mac address="52:54:00:35:be:e2"/>
      <model type="e1000e"/>
    </interface>
    <console type="pty"/>
    <channel type="spicevmc">
      <target type="virtio" name="com.redhat.spice.0"/>
    </channel>
    <graphics type="spice" port="-1" tlsPort="-1" autoport="yes">
      <image compression="off"/>
    </graphics>
    <sound model="ich9"/>
    <video>
      <model type="qxl"/>
    </video>
    <hostdev mode="subsystem" type="pci" managed="yes">
      <source>
        <address domain="0" bus="1" slot="0" function="0"/>
      </source>
    </hostdev>
    <hostdev mode="subsystem" type="pci" managed="yes">
      <source>
        <address domain="0" bus="1" slot="0" function="1"/>
      </source>
    </hostdev>
    <hostdev mode="subsystem" type="pci" managed="yes">
      <source>
        <address domain="0" bus="1" slot="0" function="2"/>
      </source>
    </hostdev>
    <hostdev mode="subsystem" type="pci" managed="yes">
      <source>
        <address domain="0" bus="1" slot="0" function="3"/>
      </source>
    </hostdev>
    <redirdev bus="usb" type="spicevmc"/>
    <redirdev bus="usb" type="spicevmc"/>
  </devices>
</domain>

Results of kvm --version :

QEMU emulator version 4.2.1 (Debian 1:4.2-3ubuntu6.17) 
Copyright (c) 2003-2019 Fabrice Bellard and the QEMU Project developers

Results of lspci -knn | grep NVIDIA -A 2 :

01:00.0 VGA compatible controller [0300]: NVIDIA Corporation TU106 [GeForce RTX 2070] [10de:1f02] (rev a1)
    Subsystem: NVIDIA Corporation TU106 [GeForce RTX 2070] [10de:12fe]
    Kernel driver in use: vfio-pci
    Kernel modules: nvidiafb, nouveau, nvidia_drm, nvidia
01:00.1 Audio device [0403]: NVIDIA Corporation TU106 High Definition Audio Controller [10de:10f9] (rev a1)
    Subsystem: NVIDIA Corporation TU106 High Definition Audio Controller [10de:12fe]
    Kernel driver in use: vfio-pci
    Kernel modules: snd_hda_intel
01:00.2 USB controller [0c03]: NVIDIA Corporation TU106 USB 3.1 Host Controller [10de:1ada] (rev a1)
    Subsystem: NVIDIA Corporation TU106 USB 3.1 Host Controller [10de:12fe]
    Kernel driver in use: vfio-pci
    Kernel modules: xhci_pci
01:00.3 Serial bus controller [0c80]: NVIDIA Corporation TU106 USB Type-C UCSI Controller [10de:1adb] (rev a1)
    Subsystem: NVIDIA Corporation TU106 USB Type-C UCSI Controller [10de:12fe]
    Kernel driver in use: vfio-pci
    Kernel modules: i2c_nvidia_gpu