On Ubuntu 20.04 with KDE installed on top.
It's a bit of a complicated setup, so please bear with me.
Primary video card: Radeon 5450 --> 1 VGA monitor, 1 DVI monitor (both working perfectly)
Secondary video card: Radeon 4550 --> 2 VGA monitors (one works perfectly, the other problematic and not working)
Tertiary video card: Radeon 4550 --> 2 VGA monitors (one works perfectly, the other not detected at all)
I just upgraded to a new motherboard. Previously the 'primary' video card was onboard intel graphics, and the entire system worked perfectly under Kubuntu 20.04. Now that I've made this hardware change and reinstalled the OS, though, both of the Radeon 4550s are working perfeclty fine with the first monitor, but cannot properly detect or output to the second monitor on each card.
Also tried installing Kubuntu 20.04 (what I'd been running previously, successfully using all 6 monitors) and had exactly the same issue.
One of the 4550s just can't detect the second monitor at all. Everything on the software side tells me I have only 5 monitors connected instead of the 6 there should be. The other 4550 seems to know that there's a monitor connected, but only detects it as "DVI-2-2", with a max resolution of 1024x768. That monitor doesn't detect any signal from the video card and doesn't display anything.
Output of xrandr --listmonitors:
xrandr --listmonitors
Monitors: 5
0: +*DVI-0 2560/597x1440/336+1080+1080 DVI-0
1: +VGA-0 1920/480x1080/270+1080+0 VGA-0
2: +DVI-2-2 1024/271x768/203+1080+1080 DVI-2-2
3: +DVI-1-0 1920/510x1080/287+3640+1080 DVI-1-0
4: +DVI-1-1 1080/480x1920/270+0+1080 DVI-1-1
Output of xrandr --listproviders:
xrandr --listproviders
Providers: number : 3
Provider 0: id: 0x56 cap: 0x9, Source Output, Sink Offload crtcs: 4 outputs: 3 associated providers: 2 name:ATI Radeon HD 5450 @ pci:0000:21:00.0
Provider 1: id: 0xba cap: 0x6, Sink Output, Source Offload crtcs: 2 outputs: 3 associated providers: 1 name:ATI Radeon HD 4550 @ pci:0000:4a:00.0
Provider 2: id: 0x95 cap: 0x6, Sink Output, Source Offload crtcs: 2 outputs: 3 associated providers: 1 name:ATI Radeon HD 4550 @ pci:0000:03:00.0
Maybe this is the kick in the pants I need to finally stop using such a crazy system (and probably move to supporting the extra monitors on USB-to-VGA adapters instead) ... but it would be really nice if I could find a software solution for this and not need to buy or install any extra hardware.